trFluor?Eu DBCO

貨號1446存儲條件 在零下15度以下保存, 避免光照
規格100 ug價格3648
Ex (nm)346Em (nm)617
分子量1765.72溶劑DMSO
產品詳細介紹


簡要概述

產品基本信息

貨號:1446

產品名稱:trFluor™Eu DBCO

規格:100ug

儲存條件:-15℃避光防潮

保質期:24個月

 

產品物理化學光譜特性

分子量:1765.72

外觀:固體

溶劑:DMSO

激發波長(nm):346

發射波長(nm):617

 

產品介紹

存在于細胞,血清或其他生物流體中的許多生物化合物都是天然熒光的,因此,由于要測定的生物分子的自發熒光引起的高背景,使用常規的快速熒光團會嚴重限制測定靈敏度。長壽命熒光團與時間分辨檢測(激發和發射檢測之間的延遲)的結合使用可最大程度地減少即時熒光干擾。我們的trFluor™Eu探針可用于需要高靈敏度測定的時間分辨熒光(TRF)。與諸如Alexa Fluor或花青染料等更傳統的熒光團相比,這些trFluor™Eu探針具有較大的斯托克斯位移和極長的發射半衰期。與其他TRF化合物相比,我們的trFluor™Eu探針具有相對較高的穩定性,高發射率和與生物分子連接的能力。此外,當與生物聚合物(例如抗體)偶聯時,我們的trFluor™Eu探針對熒光猝滅不敏感。在無銅條件下,trFluor™Eu DBCO可以容易地單擊成含有疊氮基的分子。百螢生物是AAT Bioquest的中國代理商,為您提供最優質的trFluor™I DBCO。 

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參考文獻

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Discovery and Characterization of Peptide Inhibitors for Calcium and Integrin Binding Protein 1.
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Journal: ACS chemical biology (2020)

Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer Assay to Identify Novel Hit Compounds Against BCL-2.
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Revisit ligand-receptor interaction at the human vasopressin V2 receptor: A kinetic perspective.
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Journal: European journal of pharmacology (2020): 173157

A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader Proteins.
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Journal: SLAS discovery : advancing life sciences R & D (2019): 693-700

A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs.
Authors: Giovinazzo, Hugh and Walker, David and Wyhs, Nicolas and Liu, Jianyong and Esopi, David M and Vaghasia, Ajay M and Jain, Yash and Bhamidipati, Akshay and Zhou, Jianya and Nelson, William G and Yegnasubramanian, Srinivasan
Journal: Oncotarget (2019): 3040-3050

Development of a High-Throughput Cul3-Keap1 Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Identifying Nrf2 Activators.
Authors: Poore, Derek D and Hofmann, Glenn and Wolfe, Lawrence A and Qi, Hongwei and Jiang, Ming and Fischer, Michael and Wu, Zining and Sweitzer, Thomas D and Chakravorty, Subhas and Donovan, Brian and Li, Hu
Journal: SLAS discovery : advancing life sciences R & D (2019): 175-189

LFRET, a novel rapid assay for anti-tissue transglutaminase antibody detection.
Authors: Rusanen, Juuso and Toivonen, Anne and Hepojoki, Jussi and Hepojoki, Satu and Arikoski, Pekka and Heikkinen, Markku and Vaarala, Outi and Ilonen, Jorma and Hedman, Klaus
Journal: PloS one (2019): e0225851

Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
Authors: Miller, Thomas W and Amason, Joshua D and Garcin, Elsa D and Lamy, Laurence and Dranchak, Patricia K and Macarthur, Ryan and Braisted, John and Rubin, Jeffrey S and Burgess, Teresa L and Farrell, Catherine L and Roberts, David D and Inglese, James
Journal: PloS one (2019): e0218897

Development of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic Activity.
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Journal: SLAS discovery : advancing life sciences R & D (2018): 941-950



說明書
trFluor?Eu DBCO.pdf


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