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羅丹明123 CAS 62669-70-9

貨號22210存儲條件 在零下15度以下保存, 避免光照
規格25 mg價格984
Ex (nm)508Em (nm)528
分子量380.82溶劑DMSO
產品詳細介紹


簡要概述

產品基本信息

貨號:22210

產品名稱:羅丹明123 CAS 62669-70-9

規格:25mg

儲存條件:-15℃避光防潮

保質期:12個月

 

產品物理化學光譜特性

分子量:380.82

溶劑:DMSO

激發波長(nm):507

發射波長(nm):529

 

產品介紹

羅丹明123是美國AAT Bioquest生產的羅丹明染料。帶正電荷的羅丹明染料(如羅丹明酯和羅丹明)選擇性地定位于線粒體中,因此它們廣泛用于標記活細胞的線粒體。其中羅丹明123是最常用的線粒體染色劑。它用于染色各種細胞,包括植物細胞和細菌。與JC-1一樣,羅丹明123除了用于選擇性線粒體染色外,還用于測量線粒體膜電位。由于羅丹明123選擇性地定位于癌細胞,因此可以使用羅丹明123來檢測癌細胞,并且其熒光與線粒體分布的改變密切相關。羅丹明123通常用于流式細胞術中作為Pgp的功能性報道分子。最近的報道表明羅丹明123也可以是MRP1的底物。MDR蛋白的功能測定是癌癥治療中比MDR蛋白表達水平更好的預后指標。與羅丹明123類似的羅丹明123的光譜特性使得羅丹明123的使用非常方便,因為幾乎所有熒光儀器都??配備有激發源和FITC濾光片組。羅丹明123可用于多參數分析,無需熒光干擾,與常見的蛋白質標記染料如PE-Cy5和AMCA結合使用。百螢生物是AAT Bioquest的中國代理商,為您提供最優質的羅丹明123。 

點擊查看光譜

 

參考文獻

Relationship between excretion clearance of rhodamine 123 and P-glycoprotein (Pgp) expression induced by representative Pgp inducers
Authors: Kageyama M, Fukushima K, Togawa T, Fujimoto K, Taki M, Nishimura A, Ito Y, Sugioka N, Shibata N, Takada K.
Journal: Biol Pharm Bull (2006): 779

Rhodamine 123 permeability through the catfish intestinal wall: Relationship to thermal acclimation and acute temperature change
Authors: Kleinow KM, Johnston BD, Holmes EP, McCarrol ME.
Journal: Comp Biochem Physiol C Toxicol Pharmacol (2006): 205

[Determination of rhodamine 123 in cell lysate by high-performance liquid chromatography with visible wavelength detection]
Authors: Song JP.
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban (2006): 610

Alterations in respiration rate of isolated rainbow trout hepatocytes exposed to the P-glycoprotein substrate rhodamine 123
Authors: Bains OS, Kennedy CJ.
Journal: Toxicology (2005): 87

Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes
Authors: Annaert PP, Brouwer KL.
Journal: Drug Metab Dispos (2005): 388

Determination of Rhodamine 123 in cell lysate by HPLC with visible wavelength detection
Authors: Iqbal T, Kinjo M, Dowling TC.
Journal: J Chromatogr B Analyt Technol Biomed Life Sci (2005): 259

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs
Authors: Lugo MR, Sharom FJ.
Journal: Biochemistry (2005): 14020

Isolation and enrichment of murine spermatogonial stem cells using rhodamine 123 mitochondrial dye
Authors: Lo KC, Brugh VM, 3rd, Parker M, Lamb DJ.
Journal: Biol Reprod (2005): 767

Photophysical, photochemical, and tumor-selectivity properties of bromine derivatives of rhodamine-123
Authors: Lacerda SH, Abraham B, Stringfellow TC, Indig GL.
Journal: Photochem Photobiol (2005): 1430

Rhodamine-123: therapy for hormone refractory prostate cancer, a phase I clinical trial
Authors: Jones LW, Narayan KS, Shapiro CE, Sweatman TW.
Journal: J Chemother (2005): 435

 

相關產品

產品名稱 貨號
羅丹明B CAS 81-88-9 Cat#69
羅丹明6G CAS 989-38-8 Cat#70
羅丹明110 CAS 13558-31-1 Cat#86


說明書
羅丹明123 CAS 62669-70-9.pdf


欧美精品黑人粗大
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